Superior Source Vitamins Extra Strength Vitamin D3 10,000 IU Instant Dissolve Tablet

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Ingredients & Description

Vitamin D3 works in conjunction with Calcium to help develop and maintain strong bones and teeth. Superior Source offers a new Extra Strength 10,000 IU Vitamin D which can help to ensure optimal health, as stated in a recent review study. All Superior Source Vitamin D products are D3, the finest source.

Supplement Facts Serving Size: 1 tablet
	APS	%DV
Vitamin D3 (as Cholecalciferol)	10,000 IU	2500%

* Based on a 2,000 calorie diet

** Daily Values not established

Other Ingredients: Lactose (milk sugar) and Acacia Gum

Suggested Use: Dissolve one tablet under the tongue daily as a dietary supplement. May also be swallowed as you would a regular tablet.

**These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or prevent any disease.

The tolerable upper intake level for oral vitamin D3 should be increased five-fold, experts from the US-based Council for Responsible Nutrition (CRN) have said after a review of the science. The risk assessment provides companies with a guide for safe upper levels for product formulations, and consumers with vital information on safe dosage levels from products. "This risk assessment was needed to show that newer evidence supports the conclusion that vitamin D is much safer then previously thought, particularly because of all the emergence research that shows benefit for vitamin D at higher levels than consumers were traditionally taking," lead author John Hathcock said.

Currently, the tolerable upper intake level (UL) in Europe and the US is set at 2000 International Units (IU), equivalent to 50 micrograms per day. However, recent research, particularly from clinical trials, suggests that this should be raised. The CRN scientists state that this could be raised to 10,000 IU (250 micrograms per day). The reviewers, from the CRN, Mount Sinai Hospital in Toronto and Crieghton University in Nebraska, pooled data from 21 clinical trials using doses ranging from 10 to 2500 micrograms (100,000 IU). The risk assessment also included data from animal studies, some of which used "extraordinarily high doses of vitamin D3".

"The lack of adverse effects in clinical trials that used intake up to 1250 micrograms [50,000 IU] vitamin D per day and the lack of adverse effects at lower doses inspires a high level of confidence in the data from the strongly designed clinical trials that used 250 micrograms [10,000 IU] vitamin D per day," said the reviewers. The researchers also note that for practically all the reported cases of vitamin D toxicity have involved doses that were in excess of those studied in the clinical trials. "Newer clinical trial data are sufficient to show that vitamin D is not toxic at intakes much higher than previously considered unsafe," said the reviewers.

Vitamin D is made by the body on exposure to sunshine, or can be consumed in small amounts in milk, fish, liver and egg yolk. However because of the low amounts present in the diet, and lack of sunshine in northern climates, with some estimates claiming that as much as 60 percent of northern populations may be vitamin D deficient. The reviewers note that normal dietary sources provide about 2.5 micrograms per day, while this can be increased up to 10 micrograms with fortified foods. Dietary supplements would provide higher doses. "We applied the same method to our risk assessment as the Food and Nutrition Board had used years ago, and our results concluded vitamin D could be safely taken in much higher amounts," Hathcock said.

Source

J.N. Hathcock, A. Shao, R. Vieth, R. Heaney. Risk assessment for vitamin D. American Journal of Clinical Nutrition; January 2007, Volume 85, Pages 6-18.

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Questions and answers:

Answer Vote down Vote up 0 0

Asked on: April 19, 2013
Question: I am a UK resident. I am to be prescribed 20,000 iu per day for 7 days to bring my levels. Only problem, ever since been suffering from vit d defeciency, one of my problems is dysphagia (tightening of throat muscles )had to swallow. Feel like Im going to choke on everything. Fear of taking pills. Vitamin D is not really liscensed for prescription use in the UK so not available. Would I be ok to take this in the dose reccomended by the doctor here? Is American iu the same as UK iu?


• 0 0 A: IU's should be the same in each country however you might want to confirm that with your physician. Unfortunately I cannot provide any feedback on the dose your doctor has suggested for you as I am only able to suggest what the manufactured provides which is one 10,000 IU tablet. Your physician however may advise you differently. I would definitely let your physician know how you are feeling so they are aware of the symptoms you are describing.  Vote down - Vote up

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