Coq10 | A Poweful Coenzyme Antioxidant for Heart Health

Coenzyme Q10 (CoQ10)

Coenzyme Q10 (2,3 dimethoxy-5 methyl-6-decaprenyl benzoquinone) is a fat-soluble, vitamin-like quinone also recognized under the names ubiquinone, CoQ, and vitamin Q10. The compound, CoQ10, occurs naturally in the body and is found in each individual, human cell. CoQ10's alternate name, ubiquinone, comes from the word ubiquitous, which means "found everywhere." Coenzyme Q10 was originally identified in 1957 by researchers from the University of Wisconsin in beef mitochondria. It is found in the highest concentrations in tissues such as the heart, brain, liver, and kidney due to their rapid turnover of energy. Coenzyme Q10 is key to multiple processes in the human body related to energy metabolism. Coenzyme Q10 is noted for being most beneficial in the treatment of cardiac, neurological, oncology, and immunologic disorders. This is due to the fact that these kinds of disorders are linked to dysfunctional energy metabolism, which can be directly impacted by the use of CoQ10.

Benefits of CoQ10

Coenzyme Q10 is particularly valuable in helping to treat symptoms and disorders that are benefited by mitochondrial cell support as well as antioxidant support. The most recognized uses for CoQ10 are for neurodegenerative disorders such as Parkinson's disease and certain encephalomyopathies. Coenzyme Q10 has gained orphan drug status concerning its treatment of Parkinson's and encephalomyopathies. It is also promising for its efficacy in the treatment of congestive heart failure and diabetes. It has been found to promote overall cardiovascular health. CoQ10 has been found to significantly decrease the intensity and frequency of migraine headaches as well. It can also be beneficial for people taking statin drugs or HMG-CoA reductase inhibitors, as these kinds of drugs can deplete the body of CoQ10 levels. Additionally, CoQ10 has been recognized for its ability to improve energy levels through increased energy production. Consequently, it promotes a feeling of wellness and can aid in weight loss efforts. Finally, there is some evidence that CoQ10 can aid in the treatment of gum disease (periodontitis).

How Coenzyme Q10 Works

Coenzyme Q10 works in several important ways to promote overall health and provide its many benefits for the body. It plays a crucial role in the transfer of electrons within the cells mitochondrial oxidative respiratory chain, whose main function is adenosine triphosphate production (ATP). ATP is the fuel that the body uses to produce energy and support every cellular action in the human body. Additionally, CoQ10 aids this process by helping to prevent the depletion of adenine nucleotide pool from cardiac cells. Coenzyme Q10 is also a powerful antioxidant that works to prevent lipid peroxidation while it scavenges damaging free radicals throughout the body. It also helps to decrease calcium overload by stabilizing calcium channels in the body.

Research for CoQ10

Cardiovascular Health

CoQ10 levels have been found to be low in people suffering from heart failure. According to some research, the symptoms associated with heart failure such as difficulty sleeping, shortness of breath, and swelling have been found decrease with the use of CoQ10. It is believed that CoQ10 works to strengthen the hearts pumping action by increasing the energy production of the heart muscle. However, this research is still somewhat inconclusive.

CoQ10 was administered in one study analyzing 641 people with congestive heart failure. The patients were randomized to receive either CoQ10 (2 mg per kg body weight) or a placebo plus standard treatment. People who took the CoQ10 had a significant reduction in symptom severity and fewer hospitalizations.

In a prospective, double blind study, 32 patients with end-stage heart failure awaiting heart transplantation received either 60 mg of CoQ10 or a placebo for 3 months. Patients who took the CoQ10 experienced a significant improvement in functional status, clinical symptoms, and quality of life. The study group showed significant improvement in the 6-min walk test and a decrease in dyspnea, New York Heart Association (NYHA) classification, nocturia, and fatigue. However, echocardiogram (heart ultrasound) did not indicate change nor did other objective markers.

Another study evaluated 55 patients with congestive heart failure who were given either 200 mg of CoQ10 per day or placebo. The patients were also given standard treatment. Serum levels of CoQ10 increased in patients who were given the supplement. However, CoQ10 was not found to impact ejection fraction, peak oxygen consumption, or exercise duration.

A long-term study investigating the value of CoQ10 in 79 patients suffering from stable chronic congestive heart failure showed a mild improvement in quality of life and maximum capacity for exercise compared with the placebo. The patients were given standard treatment for their condition in addition to CoQ10 supplementation.

There have also been several small trials performed using CoQ10 in the treatment of Cardiomyopathy that have shown promise.

Parkinson's disease

Evidence has indicated that CoQ10 levels may be low in people with Parkinsons disease. It is believed that CoQ10 can help to increase production of the neurotransmitter, dopamine. Dopamine is thought to be lower in people suffering from Parkinsons and could play a crucial role in improving neurological function. The antioxidant benefits of CoQ10 also work to protect the brains cells from continued damage and degeneration by free radicals.

One randomized, double-blind, placebo-controlled, multicenter study evaluated 80 patients with early stage Parkinsons disease. The patients were given 300, 600, or 1,200 mg per day of Coenzyme Q10. The study showed that CoQ10 was associated with up to 44 percent less functional decline in patients with Parkinson's disease, including activities of daily living. This was in comparison to those who were given a placebo.

Another study of 28 patients with Parkinson's disease was performed giving patients 360 mg of CoQ10 daily. The patients demonstrated mild, but significant symptom improvement. These results still need to be confirmed.

Mitochondrial Encephalomyopathies

Studies performed on 8-44 patients have indicated the ability of CoQ10 to help reduce the symptoms associated with selected mitochondrial abnormalities. Specifically, CoQ10 has been noted for its impact on mitochondrial encephalopathy, lactic acidosis, and stroke-like episodes (MELAS) syndrome, Kearns-Sayre syndrome, and myoclonus epilepsy with ragged-red fibers (MERRF) syndrome. Results were found to be more significant after 6 months of treatment.

Diabetes

One randomized, controlled trial lasting 12 weeks evaluated 74 people with type 2 diabetes. The patients were given either 100 mg of CoQ10 twice daily, 200 mg per day of fenofibrate (a drug that regulates blood lipids), both medications, or neither. CoQ10 supplementation significantly improved blood pressure and glycemic control. However, two other studies found that CoQ10 supplementation did not demonstrate any effect on glycemic control.

Migraine Headaches

A preliminary trial evaluating 32 patients taking 150 mg of coenzyme Q10 per day demonstrated the ability of CoQ10 to reduce the frequency of migraine incidences.

A similar result was identified in a randomized, double-blind, placebo-controlled trial of 42 patients. One group was given 300 mg of Coenzyme Q10 each day. The decrease in headache frequency by 50 percent or more was 47.6 percent of the people in the group given Coenzyme Q10. The response rate was only 14.4 percent in the placebo group.

CoQ10 and Prescription Drugs

Statin drugs and HMG-CoA reductase inhibitors are often used to lower cholesterol in patients. Evidence has shown that these types of drugs can interfere with the bodys ability to adequately produce CoQ10. Research has indicated that CoQ10 supplementation can be beneficial for those taking certain prescription drugs.

Gum Disease

Ten male periodontitis (gum disease) patients with 30 periodontal pockets were selected for a small study analyzing the topical application of CoQ10. The patients applied topical CoQ10 for three weeks to the periodontal pockets. The patients experienced significant improvement in symptoms.

Dosaging

The normal, recommended dosage of CoQ10 is 30 to 90 mg per day. It should be taken in divided doses. An effective and safe dose can be as high as 200 mg per day. However, you should always consult with your physician before taking any new medication or supplements. Your physician can also direct you to the most effective dosage of CoQ10, which may be even higher than 200 mg. CoQ10 is fat-soluble and is better absorbed when taken with a meal that contains fat or oil.

For the treatment of gum disease, you can apply 85 milligrams of CoQ10 per milliliter of soybean oil suspension to the surface of the affected area. Apply the tonic once weekly using a plastic syringe.

The full efficacy and results of CoQ10 is not always immediate and may take up to eight weeks to see its effects.

Side Effects

Coenzyme Q10 is largely considered to be safe and has not demonstrated any serious contraindications. A very small percentage of patients experienced potential negative side effects of diarrhea and rash. CoQ10 is meant to be used in combination with standard treatment. It is not intended to replace conventional treatment. CoQ10 has been found to lower blood sugar levels. Consequently, those who are diabetic should always use CoQ10 under the supervision of a physician. CoQ10 may also lower blood pressure. There has not been enough research to establish the safety of CoQ10 for pregnant or breastfeeding women. It is not recommended that pregnant or breastfeeding women take CoQ10 unless otherwise directed by a doctor.

 

Orachel


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Carlson Labs
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omegaQ10


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Futurebiotics
Pressur-Lo is a broad-spectrum formula packed with an array of nutrients, botanicals and other key factors to nutritionally support cardiovascular function, with a particular emphasis on nutritionally supporting healthy blood pressure levels within the normal range.
 

CoQ10 100mg


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Nature's Way
Nature's Way CoQ10, with enhanced absorption and bioavailability, is a powerful antioxidant neccessary for normal heart function and cellular energy production
 

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Nature's Way
Nature's Way CoQ10 is a necessary substance for normal heart function. CoQ10 is vital for cellular energy production and is a powerful antioxidant and free radical scavenger. Softgel delivery is ideal for CoQ10 absorption and utilization because of its solubility in oil.
 

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Seacoast Coenzyme Q10 (CoQ10), each softgel contains 120 mg of CoQ10 (Ubiquinone)
 

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Seacoast Coenzyme Q10 (CoQ10) 30 mg, 60 Softgels. Coenzyme Q10 is a normal and essential component of the membranes of mitochondria (the intracellular organelles that manufacture ATP), the basic energy molecule of the cell.
 

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Seacoast Vitamins
Seacoast Coenzyme Q10 (CoQ10) is a normal and essential component of the membranes of mitochondria (the intracellular organelles that manufacture ATP), the basic energy molecule of the cell.
 

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(60 caps), Trace Mineral Research
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Coenzyme Q10 (CoQ10) promotes cardiovascular health, is a powerful antioxidant, and supports ATP production - fuel for your body.
 

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(100 mg - 60 caps), Ultra Laboratories
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Ultra Laboratories
Low levels of Coenzyme Q10, CoQ10, are detected in patients diagnosed with chronic diseases such as heart conditions,diabetes, Parkinsons disease, muscular dystrophies, cancer and HIV/AIDS. Some prescription drugs may also reduce CoQ10 levels.Supplementation of Coenzym Q10 may help reduce incidence of these diseases.
 

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Essential for energy production at the cellular level, supplemental CoQ10 supports heart and cardiovascular health by replenishing CoQ10 levels that naturally decrease with age.
 

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Essential for energy production at the cellular level, supplemental CoQ10 supports heart and cardiovascular health by replenishing CoQ10 levels that naturally decrease with age.
 

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(120 capsules), TwinLab
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Ubiquinol CoQ10


(100mg, 150 softgels), Healthy Origins
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Healthy Origins
Kaneka QH Ubiquinol, active form of CoEnzyme Q10, which benefits your natural energy and vitality. Everyday Best Value, 150 capsules of Ubiquinol 100mg.
 

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(100mg 60 Softgel), Country Life
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Country Life
Country Life's Carni Q-Gel is hydrosoluble and employs the patented BioSolv delivery system U.S. Patent No. 6,056,971 under an exclusive agreement with Biosytes, USA Inc. This delivery system enhances absorption 300% over that found with CoQ10 tablets, hard shell capsules or other softgels tested. Supports the conversion of fat into energy. Supports normal cardiovascular function.
 

Mega CoQ10


(100mg 90 Softgel), Country Life
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Country Life
Country Life's Carni Q-Gel is hydrosoluble and employs the patented BioSolv delivery system U.S. Patent No. 6,056,971 under an exclusive agreement with Biosytes, USA Inc. This delivery system enhances absorption 300% over that found with CoQ10 tablets, hard shell capsules or other softgels tested. Supports the conversion of fat into energy. Supports normal cardiovascular function.
 

CoQ10 60 mg


(60 vcaps), NOW Foods
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NOW Foods
Cardiovascular Health Supports Healthy Heart Muscle Promotes Cellular Energy* Vegetarian Formula Coenzyme Q10 is a vitamin-like compound also called ubiquinone.  It is an essential component of cells and is necessary for mitochondrial energy production.  Years of research has shown that CoQ10 supports healthy cardiovascular and immune system functions in addition to its vital role in energy production.*   Read more about Coenzyme Q-10   Related Products   Product FAQ's   Read more about Cardiovascular Health from Your Health Professor
 

CoQ10 60 mg


(180 vcaps), NOW Foods
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NOW Foods
Cardiovascular Health Supports Healthy Heart Muscle Promotes Cellular Energy* Vegetarian Formula Coenzyme Q10 is a vitamin-like compound also called ubiquinone.  It is an essential component of cells and is necessary for mitochondrial energy production.  Years of research has shown that CoQ10 supports healthy cardiovascular and immune system functions in addition to its vital role in energy production.*   Read more about Coenzyme Q-10   Related Products   Product FAQ's   Read more about Cardiovascular Health from Your Health Professor
 

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(90 Softgels), NOW Foods
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NOW Foods
Cardiovascular Health Supports Healthy Heart Muscle Promotes Cellular Energy* Coenzyme Q10 is a vitamin-like compound also called ubiquinone.  It is an essential component of cells and is necessary for mitochondrial energy production.  Years of research has shown that CoQ10 supports healthy cardiovascular and immune system functions in addition to its vital role in energy production.*   Product FAQ's
 

CoQ10 200 mg


(60 vcaps), NOW Foods
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NOW Foods
Cardiovascular Health Supports Healthy Heart Muscle Promotes Cellular Energy* Vegetarian Formula Coenzyme Q10 is a vitamin-like compound also called ubiquinone.  It is an essential component of cells and is necessary for mitochondrial energy production.  Years of research has shown that CoQ10 supports healthy cardiovascular and immune system functions in addition to its vital role in energy production.*   Product FAQ's
 

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(60 Softgels), NOW Foods
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NOW Foods
Super High Potency Cardiovascular Health Supports Healthy Heart Muscle* with Lecithin & Vitamin E Coenzyme Q10 is a vitamin-like compound also called ubiquinone.  It is an essential component of cells and is necessary for mitochondrial energy production.  Years of research has shown that CoQ10 supports healthy cardiovascular and immune system functions in addition to its vital role in energy production.*   Product FAQ's
 

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(50 Softgels), NOW Foods
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NOW Foods
Cardiovascular Health Supports Healthy Heart Muscle* with Selenium & Vitamin E Coenzyme Q10 is a vitamin-like compound also called ubiquinone.  It is an essential component of cells and is necessary for mitochondrial energy production.  Years of research has shown that CoQ10 supports healthy cardiovascular and immune system functions in additions to its vital role in energy production.*   Read more about Coenzyme Q-10   Related Products   Product FAQ's   Read more about Cardiovascular Health from Your Health Professor
 

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(100 Softgels), NOW Foods
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NOW Foods
Cardiovascular Health Supports Healthy Heart Muscle* with Selenium & Vitamin E Coenzyme Q10 is a vitamin-like compound also called ubiquinone.  It is an essential component of cells and is necessary for mitochondrial energy production.  Years of research has shown that CoQ10 supports healthy cardiovascular and immune system functions in addition to its vital role in energy production.*   Read more about Coenzyme Q-10   Related Products   Product FAQ's   Read more about Cardiovascular Health from Your Health Professor
 

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(200 Softgels), NOW Foods
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30% Off

NOW Foods
Cardiovascular Health Supports Healthy Heart Muscle* with Selenium & Vitamin E Coenzyme Q10 is a vitamin-like compound also called ubiquinone.  It is an essential component of cells and is necessary for mitochondrial energy production.  Years of research has shown that CoQ10 supports healthy cardiovascular and immune system functions in addition to its vital role in energy production.*   Read more about Coenzyme Q-10   Related Products   Product FAQ's   Read more about Cardiovascular Health from Your Health Professor  
 

CoQ10 200 mg


(90 Lozenges), NOW Foods
CoQ10 200 mg (90 Lozenges) NOW Foods


From $31.76 
41% Off
 $37.37 
30% Off

NOW Foods
Chewable Cardiovascular Health Supports Healthy Heart Muscle* with Vitamin E & Lecithin Vegetarian Formula Coenzyme Q10 is a vitamin-like compound also called ubiquinone.  It is an essential component of cells and is necessary for mitochondrial energy production.  Years of research has shown that CoQ10 supports healthy cardiovascular and immune system functions in addition to its vital role in energy production.*   Read more about Coenzyme Q-10   Related Products   Product FAQ's   Read more about Cardiovascular Health from Your Health Professor      
 

CoQ10 400 mg


(60 Softgels), NOW Foods
CoQ10 400 mg (60 Softgels) NOW Foods


From $41.18 
41% Off
 $48.45 
30% Off

NOW Foods
High Potency Cardiovascular Health Supports Healthy Heart Muscle* with Lecithin & Vitamin E Coenzyme Q10 is a vitamin-like compound also called ubiquinone.  It is an essential component of cells and is necessary for mitochondrial energy production.  Years of research has shown that CoQ10 supports healthy cardiovascular and immune system functions in addition to its vital role in energy production.*   Read more about Coenzyme Q-10   Related Products   Product FAQ's Read more about Cardiovascular Health from Your Health Professor
 

CoQ10 400 mg


(30 Softgels), NOW Foods
CoQ10 400 mg (30 Softgels) NOW Foods


From $23.53 
41% Off
 $27.68 
30% Off

NOW Foods
High Potency Cardiovascular Health Supports Healthy Heart Muscle* with Lecithin & Vitamin E Coenzyme Q10 is a vitamin-like compound also called ubiquinone.  It is an essential component of cells and is necessary for mitochondrial energy production.  Years of research has shown that CoQ10 supports healthy cardiovascular and immune system functions in addition to its vital role in energy production.*   Read more about Coenzyme Q-10   Product FAQ's   Read more about Cardiovascular Health from Your Health Professor   Related Products
 

CoQ10 100 mg


(50 Softgels), NOW Foods
CoQ10 100 mg (50 Softgels) NOW Foods


From $12.94 
41% Off
 $15.22 
30% Off

NOW Foods
Cardiovascular Health Supports Healthy Heart Muscle Promotes Cellular Energy* Coenzyme Q10 is a vitamin-like compound also called ubiquinone.  It is an essential component of cells and is necessary for mitochondrial energy production.  Years of research has shown that CoQ10 supports healthy cardiovascular and immune system functions in addition to its vital role in energy production.*   Read more about Coenzyme Q-10   Related Products   Product FAQ's   Read more about Cardiovascular Health from Your Health Professor
 

CoQ10 100 mg


(150 Softgels), NOW Foods
CoQ10 100 mg  (150 Softgels) NOW Foods


From $32.94 
41% Off
 $38.75 
30% Off

NOW Foods
Cardiovascular Health Supports Healthy Heart Muscle Promotes Cellular Energy* Coenzyme Q10 is a vitamin-like compound also called ubiquinone.  It is an essential component of cells and is necessary for mitochondrial energy production.  Years of research has shown that CoQ10 supports healthy cardiovascular and immune system functions in addition to its vital role in energy production.*   Read more about Coenzyme Q-10   Related Products   Product FAQ's Read more about Cardiovascular Health from Your Health Professor
 

Maxi-Sorb CoQ10 30mg


(120 VCaps), Country Life
Maxi-Sorb CoQ10 30mg (120 VCaps) Country Life


From $26.14 
47% Off
 $30.75 
38% Off

Country Life
Country Life Maxi-Sorb CoQ10 provides enhanced bioavailability and triple absorption through it's patented BioSolv delivery system.
 

CoQ10 plus Lecithin


(150 mg 30 Vcaps), NOW Foods
CoQ10 plus Lecithin (150 mg 30 Vcaps) NOW Foods


From $13.80 
37% Off
 $16.23 
26% Off

NOW Foods
Now CoQ10 is Pharmaceutical (USP) Grade. NOW uses only the 100% natural, all-trans form of CoQ10.
 

Super Ubiquinol CoQ10 100 mg


(60 SGels), Life Extension
Super Ubiquinol CoQ10 100 mg (60 SGels)* Life Extension


Less than $42.10 
Too low to show!
 $42.10 
24% Off

Life Extension
Super Ubiquinol CoQ10 from Life Extension provides the body with 100 mg of the most bioactive form of CoQ10 and protects the body from damaging effects of free radicals.
 

High Absorption CoQ10


(100 mg) (120 softgels), Doctor's Best
High Absorption CoQ10 (100 mg) (120 softgels) Doctor's Best


From $15.85 
53% Off
 $18.65 
45% Off

Doctor's Best
CoQ10 has a broad range of applications, from its ability to support the heart and cardiovascular system, to the immune system and cellular energy production ad further on to the liver, nerves and muscles.