SAMe, short for S-adenosyl-methionine, is a coenzyme which is naturally synthesized in the body.Discovered in 1952, SAME has been found to play essential rolls in three metabolic processes within the body including polyamine synthesis, methylation, and trans-sulfuration, Essentially, SAMe has been found to promote healthy cell growth, gene expression, nerve regeneration, and aid in molecular activation and synthesis.It has also been found to help prevent neurodegenerative diseases such as dementia, and Alzheimer’s Disease, and combats depression, osteoarthritis, and certain liver disorders.
SAMe is necessary for the production of hormones, proteins (enzymes), nucleic acids, and neurotransmitters such as dopamine and serotonin.Recent clinical studies have shown SAMe to be effective in alleviating symptoms of depression, helping to maintain a stable mood and positive attitude.A study completed in 2002 also found SAMe to help maintain joint function, reducing pain and upholding joint elasticity and integrity. Many other studies also suggest that healthy levels of SAMe can help prevent Alzheimer’s Disease, reducing oxidative stress on/in the brain and retaining cognitive function and ability.
Helps Produce Neurotransmitters
Alleviates Symptoms of Depression
Reduces Risk of Liver Damage
Reduces Pain of Osteoarthritis
Helps Prevent Alzheimer’s Disease
Enteric Coated Tablets for Maximum Absorption & Benefits
For best results take one tablet two to three times daily in divided doses morning, midday, and late afternoon or as directed by your healthcare professional. In some cases doses exceeding 400 mg of SAMe have been found to cause dry mouth, restlessness and gastrointestinal problems. Slowly increasing dosage may help prevent these problems; taking SAMe with food may avoid gastrointestinal upsets. SAMe works well when combined with B12, B6 and Folic Acid.
SAMe is not recommended for people who have been diagnosed with bipolar disorder.
SAMe Serving Size: 1 Enteric Coated Tablet
APS = Amount Per Serving *% Daily Value (%DV) not established.
*Not intended to diagnose or treat diseases or ailments, and is not reviewed by the
Uses & Indications.
Enhancing Immune Function
Ailments & Concerns.
Questions and answers:
Asked on: January 18, 2013 Question: can same be taken with food
00A: Thank you for contacting us about SAMe. Yes, taking SAMe with food may avoid gastrointestinal upsets. SAMe works well when combined with B12, B6 and Folic Acid.
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Asked on: February 7, 2013 Question: why is it reccomended not to take if you have bipolar ??
00A: Thank you for your interest in SAMe. Bipolar disorder is characterized by states of mania and depression. We put the caution on SAMe due to the potential for individuals with bipolar disorder to have an increased risk of experiencing manic episodes. It is important to keep in mind that every individual has a unique biochemical makeup so not every person will respond the same way.
If an individual has been diagnosed with bipolar disorder, we encourage them to discuss with their doctor before adding nutritional supplements to their regimen.
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